The use of Marijuana by pregnant mothers is also seemed to be a cause of later-on schizophrenia (Nolen-Hoeksema & Rector, 2015, p. 766).. Although it is not a single gene rather multiple genes are involved. Also, antipsychotic medications that block the action of the neurotransmitter dopamine can effectively reduce symptoms. For different people, schizophrenia can involve different clusters of symptoms. The research that geneticists and other medical professionals have conducted provides evidence as to why schizophrenia is linked to specific cerebral and physical symptoms, not other causes, such as behavior that is reinforced. What are the Factors and Causes of Schizophrenia ? Excessive synaptic pruning during adolescence and early adulthood, due to increased complement (C4) activity, could lead to the cognitive symptoms seen in schizophrenia. Viral infection leading to brain dysfunction: more prevalent than appreciated?. Get the latest public health information from CDC: Instead, scientists are looking for underlying differences among these groups of people that can explain why they experience different levels of risk. Schizophrenia: a pathogenetic autoimmune disease caused by viruses and pathogens and dependent on genes. The evidence of a genetic predisposition to schizophrenia is overwhelming. This suggests something else must cause schizophrenia as well; otherwise the drugs would help all the patients. Learn the best ways to manage stress and negativity in your life. Cognitive explanation suggests that this disorder is not a domain-specific deficit rather it is an impairment related to the complete integration of brain function. Whalley HC, Gountouna VE, Hall J, McIntosh AM, Simonotto E, Job DE, Owens DG, Johnstone EC, Lawrie SM. Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. Because the causes of schizophrenia have been so difficult to define, much research has been devoted to investigating societal issues that could potentially contribute to the onset of the disease in some people. One is that antipsychotic drugs, which block dopamine receptor don’t always help patients. What Are the Symptoms of Disorganized Schizophrenia? However, genes alone don’t cause schizophrenia. Copyright 2003-2019 | Academic Master is a trading name of HighEnd Technologies LTD. Every essay on this website is copyrighted by Academic Master. COVID-19 is an emerging, rapidly evolving situation. However, no twin research has found a 100% concordance rate; therefore it is impossible the say that genes definitely cause schizophrenia, as other factors clearly have an influence. The brain imaging scans support this explanation in itself, it’s clear that a lot of schizophrenics have different brain structures to normal people, so there must be some correlation between the two. The precise and accurate causes of schizophrenia are unknown. American Psychiatric Association. Basal ganglia contain a wide variety of modulators and neurotransmitters that are richly innervated by the structure of the brain, so if any alteration occurs in the basal ganglia then this could change the frontal cortical function via these long tract pathways (Nolen-Hoeksema & Rector, 2015, p. 766). If your brother or sister or one parent has the illness, your chance of having schizophrenia is around 10 percent. Schizophrenia causes the schizophrenia is a syndrome that can affect thinking, perception, speech and movement of the affected person. Early-life metal exposure and schizophrenia: A proof-of-concept study using novel tooth-matrix biomarkers. According to some laboratory findings, decrease volume of superior temporal gyrus has been observed during the episodes of illness.

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